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ONX1801.000-C PROACT Xa - A prospective, randomized, active (warfarin) controlled, parallel-arm clinical trial to determine if patients with an On-X aortic valve can be maintained safely and effectively on the factor Xa inhibitor apixaban

NCT04142658

PROACT Xa - A prospective, randomized, active (warfarin) controlled, parallel-arm clinical trial to determine if patients with an On-X aortic valve can be maintained safely and effectively on the factor Xa inhibitor apixaban

Associated Conditions

Coagulation

Principal Investigator

Sponsor

CryoLife

You are being asked to take part in this research study because you are at least 18 years old, have had an On-X mechanical valve implanted in the aortic position at least 3 months (90 days) ago, are currently receiving warfarin anticoagulation, and are able to receive warfarin with a target INR of 2.0 to 3.0.

This study is currently enrolling.