To compare V940 plus pembrolizumab to placebo plus pembrolizumab with respect to DFS. Hypothesis (H1): V940 plus pembrolizumab is superior to placebo plus pembrolizumab with respect to DFS as assessed by the investigator ...

This clinical trial is being performed because there is a need for safer and more effective treatments for glioblastomas. The purpose of this specific clinical study is to determine how safe and effective TVI-Brain-1 would be a ...

The purpose of this study is to test the safety of an investigational (experimental) drug, TAC-001, to see what affects it has on patients with cancer. TAC-001 is considered investigational in this study because it has not been ...

This study is being done to answer the following question: Among patients with early-stage TNBC who achieve a pCR after preoperative chemotherapy in combination with pembrolizumab, will observation after surgery be as effective ...

The primary objective of the study is to demonstrate that epcoritamab with R2 (ER2) will improve CR30 rates compared to chemoimmunotherapy

The main purpose of this study is to investigate the safety, effectiveness, and tolerability (whether side effects can be handled by a participant) of ficlatuzumab at two different doses when given with the established dose of ...

Study Purpose: The purposes of this study are to look at the effect of the study drug compared to placebo (a drug that looks like the study drug but has no active medicine) on calorie intake, different uses of energy in the bod ...

Objectives: Primary: Dose Escalation: To identify the recommended doses for expansion (RDEs) of NKT3447 in adult subjects with advanced/metastatic solid tumors Dose Expansion: To evaluate the preliminary antitumor activity of N ...

Madrigal Pharmaceuticals, Inc. has begun a study of an investigational product (also known as the “study drug”) called resmetirom as a possible treatment for NASH cirrhosis. An investigational drug is one that has not been appr ...