Clinical Trial Search Results
A Lifetime Partnership with Patients Who Have or May be at Risk of Having Cancer (Lungs)
This study is currently enrolling.
We are asking to study your blood, bone marrow samples, tissues and other body fluids and any parts that make up these tissues, along with your clinical records and survey information. We are building a large database of inform ...
A Multi-center, Randomized, Double-blind, Placebo controlled Phase III Study to Assess the Efficacy, Safety, and Tolerability of PXT3003 in Charcot-Marie-Tooth Type 1A
This study is currently enrolling.
The main purpose of this study is to investigate how effective PXT3003 is when compared to a placebo, on the disease progression and symptoms of CMT1A. The study also aims to assess the safety and tolerability (whether side ef ...
A Phase 1, First-in-Human, Open-Label, Dose Escalation and Expansion Study of CUE-101 Monotherapy in Second Line and CUE-101 Combination Therapy with Pembrolizumab in First Line Patients with HPV16+ Recurrent/Metastatic Head and Neck Squamous Cell Carcinoma (HNSCC)
This study is currently enrolling.
Historically, patients with recurrent or metastatic head and neck cancer (HNSCC) have been treated with combinations of chemotherapeutic drugs. Recent studies with immunotherapy drugs that inhibit the programmed cell death 1 ( ...
A Phase 1, Open-Label, Multicenter, Dose Escalation Study of PRT1419 Injection in Patients with Relapsed/Refractory Hematologic Malignancies
This study is currently enrolling.
The purpose of this research study is to test the safety of PRT1419 at different dose levels to find out what effects, good and/or bad, PRT1419 has on you and your type of cancer. The information collected from you and from oth ...
A Phase 1/1b Study to Evaluate the Safety and Tolerability of AB308 in Combination with AB122 in Participants with Advanced Malignancies
This study is currently enrolling.
The purpose of the study is to help the Sponsor understand whether study drugs, AB308 together with zimberelimab (also called AB122) can be safely given to patients with the type of cancer you have. These study drugs are invest ...
A Phase 3, Multicenter, Randomized, Double-Blind, Placebo- and Active-Controlled, Treat-Through Study to Evaluate the Efficacy and Safety of Mirikizumab in Patients with Moderately to Severely Active Crohn's Disease.
This study is currently enrolling.
The main reason for you to take part in this study is not to treat you for your condition but to help in answering the following research questions: How safe mirikizumab is and whether you might have any side effects when you t ...
A Phase 3, Randomized, Open Label Study to Compare Nivolumab plus Concurrent Chemoradiotherapy (CCRT) followed by Nivolumab plus Ipilimumab or Nivolumab plus CCRT Followed by Nivolumab vs CCRT followed by Duravalumab in Previously Untreated, Locally Advanced Non-small Cell Lung Cancer (LA NSCLC)
This study is currently enrolling.
The purpose of this study is to evaluate the effectiveness (how well the drug(s) work), safety, and tolerability of adding the investigational drug, Nivolumab, to concurrent chemoradiotherapy followed by treatment with Nivoluma ...
A Phase II Open-Label Study Investigating the Efficacy, Safety and Pharmacokinetic Properties of OKN-007 Combined with Temozolomide in Patients with Recurrent Glioblastoma
This study is currently enrolling.
The main purpose of this study is to test the safety of an experimental drug called OKN‑007 when combined with an approved chemotherapy drug, temozolomide, in the treatment of brain cancer. Any effect it might have on your brai ...
A Phase II Study of Neoadjuvant Nivolumab plus Ipilimumab and Short-Course Radiation in MSI-H/dMMR Locally Advanced Rectal Adenocarcinoma
This study is currently enrolling.
To demonstrate that neoadjuvant nivolumab and ipilimumab in combination with short-course radiation will improve the pathologic complete response rate (pCR) in MSI-H/dMMR locally advanced rectal adenocarcinoma at TME.