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James P. Delany, PhD, BS

James P. Delany, PhD, BS

Senior Investigator at the Translational Research Institute

Translational Research

James DeLany

Overview

James P. DeLay, Ph.D. is a Senior Investigator at the Translational Research Institute. He earned his doctoral degree from The Ohio State University in 1986 followed by postdoctoral training with Dr. Schoeller in the doubly labeled water (DLW) method. In 1989 he set up a stable isotope laboratory at the Pennington Biomedical Research Center and was a faculty member for 16 years. In 2005 he was recruited by Dr. David Kelly to the faculty at the University of Pittsburgh to expand stable isotope capabilities.

A major focus is his NIH-funded project applying PET/CT imaging to determine the role of specific steps of glucose uptake and the contribution of muscle and adipose tissue in the lower peripheral glucose uptake in African American women. He is also examining the role of mitochondrial function in racial differences in metabolic rate, aerobic fitness and glucose uptake. In another NIH-funded project he is employing DLW, indirect calorimetry, activity monitors, and dual energy x-ray absorptiometry to examine the role of energy balance in the increased obesity associated with the recently identified CREBRF missense variant in Samoans.

Dr. DeLany has published over 105 peer-reviewed scientific manuscripts. He has also served on several NIH grant review panels and serves on the ADA Research Grant Review Committee.

Articles

Source of nicotinamide governs its metabolic fate in cultured cells, mice, and humans

CELL REPORTS

2023

Resting and total energy expenditure of patients with long-chain fatty acid oxidation disorders (LC-FAODs)

MOLECULAR GENETICS AND METABOLISM

2023

Cascades of diabetes and hypertension care in Samoa: Identifying gaps in the diagnosis, treatment, and control continuum - a cross-sectional study

LANCET REGIONAL HEALTH-WESTERN PACIFIC

2022

Effect of physical activity in a weight loss program on circulating total ANGPTL8 concentrations in northern Americans with obesity: A prospective randomized controlled trial.

Nutrition, metabolism, and cardiovascular diseases : NMCD

2022

Validity of dual-energy x-ray absorptiometry for estimation of visceral adipose tissue and visceral adipose tissue change after surgery-induced weight loss in women with severe obesity

Obesity

2022

The protective effect of rs373863828 on type 2 diabetes does not operate through a body composition pathway in adult Samoans

Obesity

2022

Weight Loss and Exercise Differentially Affect Insulin Sensitivity, Body Composition, Cardiorespiratory Fitness, and Muscle Strength in Older Adults With Obesity: A Randomized Controlled Trial

JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES

2021

Corrigendum to 'Non-invasive Assessment of Liver Fat in ob/ob Mice Using Ultrasound-Induced Thermal Strain Imaging and Its Correlation with Hepatic Triglyceride Content' [Ultrasound Med Biol 47 (2021) 1067-1076].

Ultrasound in medicine & biology

2021

NON-INVASIVE ASSESSMENT OF LIVER FAT IN OB/OB MICE USING ULTRASOUND-INDUCED THERMAL STRAIN IMAGING AND ITS CORRELATION WITH HEPATIC TRIGLYCERIDE CONTENT

ULTRASOUND IN MEDICINE AND BIOLOGY

2021

The effects of hydroxychloroquine on insulin sensitivity, insulin clearance and inflammation in insulin-resistant adults: A randomized trial

DIABETES OBESITY & METABOLISM

2021

Education & Training

Education

Ohio State University, Columbus, OH

Residency

University of Pittsburgh

Specialty

Nutrition

Associated Clinical Trials