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James P. Delany, PhD, BS

James P. Delany, PhD, BS

Senior Investigator at the Translational Research Institute

Translational Research

James P. DeLany

Overview

James P. DeLay, Ph.D. is a Senior Investigator at the TRI-MD. He earned his doctoral degree from The Ohio State University in 1986 followed by postdoctoral training with Dr. Schoeller in the doubly labeled water (DLW) method. In 1989 he set up a stable isotope laboratory at the Pennington Biomedical Research Center and was a faculty member for 16 years. In 2005 he was recruited by Dr. David Kelly to the faculty at the University of Pittsburgh to expand stable isotope capabilities.

A major focus is his NIH-funded project applying PET/CT imaging to determine the role of specific steps of glucose uptake and the contribution of muscle and adipose tissue in the lower peripheral glucose uptake in African American women. He is also examining the role of mitochondrial function in racial differences in metabolic rate, aerobic fitness and glucose uptake. In another NIH-funded project he is employing DLW, indirect calorimetry, activity monitors, and dual energy x-ray absorptiometry to examine the role of energy balance in the increased obesity associated with the recently identified CREBRF missense variant in Samoans.

Dr. DeLany has published over 105 peer-reviewed scientific manuscripts. He has also served on several NIH grant review panels and serves on the ADA Research Grant Review Committee.

Articles

Decreased Mitochondrial Dynamics Is Associated with Insulin Resistance, Metabolic Rate, and Fitness in African Americans

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

2020

Bariatric Surgery vs Lifestyle Intervention for Diabetes Treatment: 5-Year Outcomes From a Randomized Trial

JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM

2020

The ZJU index is a powerful surrogate marker for NAFLD in severely obese North American women

PLOS ONE

2019

Impact of Hepatic Steatosis on Resting Metabolic Rate and Metabolic Adaptation in Response to Intentional Weight Loss

HEPATOLOGY COMMUNICATIONS

2019

Mitochondrial Respiration is Associated with Lower Energy Expenditure and Lower Aerobic Capacity in African American Women

Obesity

2018

Triheptanoin versus trioctanoin for long-chain fatty acid oxidation disorders: a double blinded, randomized controlled trial

JOURNAL OF INHERITED METABOLIC DISEASE

2017

Resting and exercise energy metabolism in weight-reduced adults with severe obesity

Obesity

2016

Education & Training

Education

Ohio State University, Columbus, OH

Residency

University of Pittsburgh

Specialty

Nutrition

Associated Clinical Trials