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Lauren M. Sparks, PhD

Lauren M. Sparks, PhD

Associate Investigator at the Translational Research Institute for Metabolism and Diabetes.

Translational Research

Lauren M. Sparks

Overview

Dr. Lauren M. Sparks is an Investigator at the Translational Research Institute for Metabolism and Diabetes. Dr. Sparks pursues investigations on the topics of exercise response variation. Dr. Sparks is interested in understanding why some individuals do not respond favorably to exercise as a means of improving their metabolism and related co-morbidities. She aims to advance the field of exercise and type 2 diabetes and potentially shift the paradigm, allowing interventions to be targeted to those individuals most likely to benefit as well as identify novel approaches to treat those who do not. Dr. Sparks investigates the communication between muscle and fat tissue and how some individuals who are obese, but metabolically healthy, differ from those individuals who are obese and metabolically unhealthy. Prior to joining the TRI-MD, Dr. Sparks was a postdoctoral scientist at Maastricht University in the Netherlands from 2009-2012. She focused on exercise and mitochondrial function in muscle and brown adipose tissue. From 2006-2009, Dr. Sparks was a postdoctoral fellow at Pennington Biomedical Research Center in Baton Rouge, Louisiana with a focus on exercise and substrate metabolism in type 2 diabetes. Dr. Lauren Sparks was born in Patterson, Louisiana. She earned a B.S. in Zoology and a B.A. in Spanish in 2002 and continued on to earn her PhD in Molecular Biology in 2006 from Louisiana State University.

Articles

An improvement in skeletal muscle mitochondrial capacity with short-term aerobic training is associated with changes in Tribbles 1 expression

PHYSIOLOGICAL REPORTS

2020

Plasma Myokine Concentrations After Acute Exercise in Non-obese and Obese Sedentary Women

FRONTIERS IN PHYSIOLOGY

2020

Endurance training remodels skeletal muscle phospholipid composition and increases intrinsic mitochondrial respiration in men with Type 2 diabetes

PHYSIOLOGICAL GENOMICS

2019

Precision exercise medicine: understanding exercise response variability

BRITISH JOURNAL OF SPORTS MEDICINE

2019

GDF15 Provides an Endocrine Signal of Nutritional Stress in Mice and Humans

CELL METABOLISM

2019

Exercise Response Variations in Skeletal Muscle PCr Recovery Rate and Insulin Sensitivity Relate to Muscle Epigenomic Profiles in Individuals With Type 2 Diabetes

DIABETES CARE

2018

HDAC11 suppresses the thermogenic program of adipose tissue via BRD2

JCI INSIGHT

2018

Elevated Nicotinamide Phosphoribosyl Transferase in Skeletal Muscle Augments Exercise Performance and Mitochondrial Respiratory Capacity Following Exercise Training

FRONTIERS IN PHYSIOLOGY

2018

Exercise training reduces intrahepatic lipid content in people with and people without nonalcoholic fatty liver

AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

2018

Genetic Markers of Brown Adipose Tissue Identity and In Vitro Brown Adipose Tissue Activity in Humans

Obesity

2018

Education & Training

Education

Louisiana State University, Baton Rouge, LA

Associated Clinical Trials