
Neuroscience Research Institute
Clinical Trials
A double-blind, randomized, placebo-controlled study to evaluate the efficacy and safety of intravenous ganaxolone in status epilepticus
This study is currently enrolling.
The purpose of this research is to find out if ganaxolone can stop or decrease the seizure activity in participants who have SE and if ganaxolone is safe compared to placebo when given to participants who are on other anti-seiz ...
A Multi-center, Randomized, Double-blind, Placebo controlled Phase III Study to Assess the Efficacy, Safety, and Tolerability of PXT3003 in Charcot-Marie-Tooth Type 1A
This study is currently enrolling.
The main purpose of this study is to investigate how effective PXT3003 is when compared to a placebo, on the disease progression and symptoms of CMT1A. The study also aims to assess the safety and tolerability (whether side ef ...
A Phase 1b/2a Randomized, Double-Blind, Placebo Controlled, Parallel Group, Dose-Escalation Study to Investigate the Safety, Tolerability, pharmacokinetics, Pharmacodynamics, and Exploratory Efficacy of LP352 in Subjects With Developmental and Epileptic Encephalopathies
This study is currently enrolling.
LP352 is being studied to see if it might reduce the number of seizures in patients with DEE. LP352 is thought to work by activating specific sites in the brain that are associated with seizure disorders.
A Phase 2, multicenter, randomized, double-blind, placebo-controlled study to evaluate the efficacy and safety of SAR443820 in adult participants with amyotrophic lateral sclerosis, followed by an open-label extension
This study is currently enrolling.
The purpose of the study is to evaluate twice daily (BID) oral doses of the investigational drug SAR443820 compared to placebo (which has no active medication) in addition to the standard of care, (e.g. riluzole or edaravone) f ...
A Phase 2b, Multicenter, Randomized, Double-Blind, Placebo-Controlled Study to Determine the Efficacy and Safety of BIIB122 in Participants with Parkinson’s Disease
This study is currently enrolling.
You may be eligible to take part in the study because you have Parkinson’s Disease (PD). Only people who have been diagnosed with PD in the past 2 years and who are within the ages of 30 to 80 years can take part in the study. ...
Amzell B.V. / A Phase 3, Randomized, Open-Label Study to Evaluate the Efficacy and Safety of AMZ002, Compared to Vigabatrin, in the Treatment of Infantile Spasms
This study is currently enrolling.
The main purpose of this study is to learn how well AMZ002 works and how safe it is compared with a similar drug called vigabatrin. Vigabatrin is a drug that is currently approved for use by the US FDA and in other countries to ...
An Open-Label, Single-Dose, Pharmacokinetics Study of VALTOCO with Open-Label Safety Period in Pediatric Subjects with Epilepsy
This study is currently enrolling.
This is a research study to evaluate the pharmacokinetics (PK), safety and tolerability after a single intranasal dose of VALTOCO (diazepam nasal spray), followed by a long-term safety period, where VALTOCO will be used “as nee ...
EMBOTRAP EXTRACTION & CLOT EVALUATION & LESION EVALUATION FOR NEUROTHROMBECTOMY
This study is currently enrolling.
The purpose of this study is to gather real world data on the performance of the EmboTrap Revascularization Device for the removal of blood clots in the setting of ischemic stroke. The EmboTrap® Revascularization Device is not ...
Isolation of Tumor Cells, Cancer Stem Cells and
Human Neuronal Stem Cells from Human Brain Tumor Tissue for Analysis of Cancer Stem Cell Markers’ Expression in Cellular Differentiation and Self-renewal for Studying the Effectiveness of Cancer Therapy with Subsequent Identification of Exosomal Biomarkers for Early Diagnostic Purposes
Human Neuronal Stem Cells from Human Brain Tumor Tissue for Analysis of Cancer Stem Cell Markers’ Expression in Cellular Differentiation and Self-renewal for Studying the Effectiveness of Cancer Therapy with Subsequent Identification of Exosomal Biomarkers for Early Diagnostic Purposes
This study is currently enrolling.
The purpose of this clinical trial is to collect and study brain tumor samples to help understand why the tumor grows back and to seek new ways to treat it.