
Translational Research Institute
Clinical Trials
ACES: Ace Inhibitors Combined with Exercise for Hypertensive Seniors
This study is currently enrolling.
The purpose of this research study is to see if regular exercise when combined with one of three commonly used high blood pressure medications can improve the physical abilities of older adults to perform their daily life activ ...
AVAIL: AdventHealth Research Institute Non-Alcoholic Fatty Liver Disease Biobank and Registry
This study is currently enrolling.
Non-alcoholic fatty liver disease (NAFLD) is a common liver disease that leads to many health complications. Many people have this disease and do not know it. There are no medications available to treat it. The purpose of this ...
BATSR: BAT as a therapeutic for the metabolic and cardiac dysfunction with senescence
This study is currently enrolling.
To obtain a better understanding of how metabolic and heart health change with aging. To be enrolled in this study, you must meet certain requirements. You may be eligible to participate if you meet the following criteria: BM ...
CASINO: Low-Carbohydrate Diet and SGLT2-Inhibitor to Achieve Moderate Ketosis in Healthy Volunteers
This study is currently enrolling.
The purpose of this study is to test the hypothesis that a low-carbohydrate diet combined with an SGLT2-inhibitor is sufficient to induce moderate ketosis in healthy volunteers. To be enrolled in this study, you must meet certa ...
COMET: ImpaCt Of shiftwork on METabolic Flexibility and Skeletal Muscle Clocks.
This study is currently enrolling.
Study Purpose: To determine how working a nighttime shift impacts your metabolism. To be enrolled in this study, you must meet certain requirements.
DREAM: Diabetes RElated to Acute pancreatitis and its Mechanisms (DREAM). An observational cohort study from the Type 1 Diabetes in Acute Pancreatitis Consortium (T1DAPC)
This study is currently enrolling.
Study Purpose: The purpose of this research study is to find out how many people with acute pancreatitis develop diabetes. Risk factors for diabetes and the types of diabetes that occur after acute pancreatitis will also be st ...
EXPET: Dynamic in vivo PET imaging and ex vivo biopsies from skeletal muscle and adipose tissue to investigate the effects of exercise on insulin resistance and mitochondrial energetics in type 2 diabetes
This study is currently enrolling.
The overall aim of this study is to investigate the effects of exercise training on skeletal muscle and adipose tissue insulin resistance in subjects with Type 2 Diabetes (T2D).
FIND-CKD: A randomized, double-blind, placebo-controlled, parallel-group, multicenter Phase 3 study to investigate the efficacy and safety of FInerenone, in addition to standard of care, on the progression of kidney disease in patients with Non-Diabetic Chronic Kidney Disease.
This study is currently enrolling.
Study Purpose: To determine the safety and efficacy of Finerenone along with standard of care, on the progression of kidney disease in patients with Non-Diabetic Chronic Kidney Disease. To be enrolled in this study, you must m ...
GLADIATOR: A phase 3, multicenter, randomized, double-blind, placebo-controlled study to assess the efficacy and safety of 400 mg twice a day oral ladarixin in patients with new-onset type 1 diabetes and a low residual β-cell function at baseline.
This study is currently enrolling.
The purpose of this study is to check and collect data of how the body absorbs, distributes and gets rid of the study drug in the blood during the first cycle of LDX0319 study treatment. These data will help improve knowledge a ...