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Anna Casu, MD

Anna Casu, MD

Associate Investigator

Translational Research

Anna Casu

Overview

Dr. Anna Casu is Associate Investigator at the Translational Research Institute and Von Weller Family Chair in Type 1 Diabetes Research. Her research focuses on type 1 diabetes (T1D) epidemiology, prediction, and pathogenic mechanisms linked to the relationship between the exocrine and endocrine pancreas and the onset of T1D in adults.
She obtained her medical degree and completed her residency and fellowship in endocrinology at the University of Cagliari, Sardinia, Italy, when she published articles about the world’s second-highest incidence rate of T1D on the island. She became a Post-Doctoral Associate, then Research Associate, at the University of Pittsburgh, then moved back to Italy where she became Chief of the Diabetes and Islet Transplantation Unit and Clinical Assistant Professor of Medicine, University of Pittsburgh Medical Center, both based in Palermo, Italy. There, she established and managed the pancreatic islet transplant unit and program, and her research was funded by the European Union.
Leveraging her knowledge of human pancreas biology, Dr. Casu’s current research interest focuses on the relationship between the exocrine and the endocrine pancreas, with an emphasis on cell-to-cell interactions and circulating biomarkers. She is the local principal investigator of the NCI-funded New-Onset Diabetes (NOD) study of the Chronic Pancreatitis Diabetes Pancreatic Cancer Consortium and co-investigator for the NIH/NIDDK funded Type 1 Diabetes in Acute Pancreatitis Consortium, where she serves as co-chair of the Immunology Working Group. She actively collaborates with AdventHealth gastroenterologists and surgeons specializing in caring for patients with disorders of the pancreas.

Articles

Impact of bariatric surgery and weight loss medications in adults with type 1 diabetes in the T1D Exchange Clinic Registry

JOURNAL OF DIABETES AND ITS COMPLICATIONS

2021

Investigation of Extracellular Vesicles From SARS-CoV-2 Infected Specimens: A Safety Perspective

FRONTIERS IN IMMUNOLOGY

2021

Surface-modified nanoerythrosomes for potential optical imaging diagnostics

JOURNAL OF COLLOID AND INTERFACE SCIENCE

2021

Pharmacological therapies to address obesity in type 1 diabetes

CURRENT OPINION IN ENDOCRINOLOGY DIABETES AND OBESITY

2020

Characteristics of adult- compared to childhood-onset type 1 diabetes

DIABETIC MEDICINE

2020

Carnosine protects pancreatic beta cells and islets against oxidative stress damage

MOLECULAR AND CELLULAR ENDOCRINOLOGY

2018

Identification of Unique Antigenic Determinants in the Amino Terminus of IA-2 (ICA512) in Childhood and Adult Autoimmune Diabetes: New Biomarker Development

DIABETES CARE

2017

Humoral Autoimmunity against the Extracellular Domain of the Neuroendocrine Autoantigen IA-2 Heightens the Risk of Type 1 Diabetes

ENDOCRINOLOGY

2010

The International Xenotransplantation Association consensus statement on conditions for undertaking clinical trials of porcine islet products in type 1 diabetes - Chapter 4: Pre-clinical efficacy and complication data required to justify a clinical trial

XENOTRANSPLANTATION

2009

Education & Training

Education

University of Caligari, Italy

Residency

University of Caligari, Italy

Fellowship

University of Caligari, Italy

Associated Clinical Trials