This is a randomized, double-blind, placebo-controlled trial, designed to evaluate the efficacy and safety of SAGE-547 administered as a continuous intravenous infusion to subjects in SRSE.

Through a chart review of children with antibodymediated autoimmune encephalitides we aim to describe: a)extent and type of neurologic manifestations at presentation, hospitalization(s), and follow up. b)improvement or resoluti ...

You are being asked to take part as a participant in a non-interventional observational registry, because you have been diagnosed with spinal muscular atrophy(SMA) and you are an adult, or your parents and or guardians consente ...

The purpose of this research is to find out if ganaxolone can stop or decrease the seizure activity in participants who have SE and if ganaxolone is safe compared to placebo when given to participants who are on other anti-seiz ...

This is a research study to evaluate the pharmacokinetics (PK), safety and tolerability after a single intranasal dose of VALTOCO (diazepam nasal spray), followed by a long-term safety period, where VALTOCO will be used “as nee ...

The main purpose of this extension study is to look at how safe STK-001 is when given every 4 months over a year. The study will also look at how well a person can tolerate receiving multiple doses of the study drug.