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Yury O. Nunez-Lopez, PhD

Yury O. Nunez-Lopez, PhD

Research Scientist

Translational Research

Yury Nunez

Overview

​Over 25 years of valuable wet lab and bioinformatic experiences. Implemented and managed the entire research workflow, from developing research ideas and writing grant proposals to designing and performing experimental procedures, conducting high throughput data analyses, and publishing results in peer reviewed journals. Established the NGS section of a Cancer Pharmacogenomics laboratory from scratch: handled the research and negotiation process to purchase NGS instrument, conducted site preparation for installation, designed and implemented pipelines for data generation using commercial software and in-house developed R scripts. Contributed advanced understandings of biological principles underlying gene and microRNA regulation, cellular pathway analysis, comparative genomics, gene coexpression networks, and statistical modeling, among others. Currently studying metabolism, obesity, diabetes, cancer, and aging. Involved in translational research in the extracellular vesicle field. Expertise in microRNA profiling, transcriptomics, and proteomics.

Articles

Extracellular vesicle proteomics and phosphoproteomics identify pathways for increased risk in patients hospitalized with COVID-19 and type 2 diabetes mellitus

DIABETES RESEARCH AND CLINICAL PRACTICE

2023

Detectable Lipidomes and Metabolomes by Different Plasma Exosome Isolation Methods in Healthy Controls and Patients with Advanced Prostate and Lung Cancer

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

2023

A comparative Proteomics Analysis Identified Differentially Expressed Proteins in Pancreatic Cancer-Associated Stellate Cell Small Extracellular Vesicles

MOLECULAR & CELLULAR PROTEOMICS

2022

Coordinated regulation of gene expression and microRNA changes in adipose tissue and circulating extracellular vesicles in response to pioglitazone treatment in humans with type 2 diabetes

FRONTIERS IN ENDOCRINOLOGY

2022

Proteomics and Phosphoproteomics of Circulating Extracellular Vesicles Provide New Insights into Diabetes Pathobiology

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

2022

Plasma miRNA Profile of Crohn's Disease and Rheumatoid Arthritis Patients

BIOLOGY-BASEL

2022

Circulating microRNA profile in humans and mice with congenital GH deficiency

AGING CELL

2021

Investigation of Extracellular Vesicles From SARS-CoV-2 Infected Specimens: A Safety Perspective

FRONTIERS IN IMMUNOLOGY

2021

Profiling of tRNA Halves and YRNA Fragments in Serum and Tissue From Oral Squamous Cell Carcinoma Patients Identify Key Role of 5 ' tRNA-Val-CAC-2-1 Half

FRONTIERS IN ONCOLOGY

2019

Predicting and understanding the response to short-term intensive insulin therapy in people with early type 2 diabetes

MOLECULAR METABOLISM

2019

Education & Training

Education

Institute of Nuclear Sciences & Technology, Cuba

Residency

Yale University School of Medicine, Research Associate

Fellowship

Rutgers University, NJ