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Richard E. Pratley

Richard E. Pratley

Senior Investigator

Pratley

Overview

Dr. Richard Pratley serves as the Samuel E. Crockett Chair in Diabetes Research, as well as Senior Investigator at the AdventHealth Translational Research Institute and Medical Director at the AdventHealth Diabetes Institute.  As a member of the American Diabetes Association, the European Association for the Study of Diabetes and The Obesity Society, Dr. Pratley continues his active involvement in the professional community.  The Henry Christian Award for Excellence in Clinical Research from the American Federation for Clinical Research Foundation was awarded in recognition of his work.  Dr. Pratley regularly presents at national and international meetings, has written over 250 peer-reviewed articles, and is a Principal Investigator for both NIH and pharmaceutical company sponsored trials in diabetes and obesity.  He has served as a member of the editorial boards of Diabetes Care, The Lancet: Diabetes and Endocrinology, The Journal of Diabetes and its Complications and The Journal of Clinical Endocrinology and Metabolism and acts as an ad hoc reviewer for many other journals.

His current research interests include the prevention of diabetes, improving the care for older persons with diabetes, developing new drugs to treat and prevent diabetes and its complications, and understanding the role of the fat cell in increasing the risk of diabetes and heart disease.

Associated Clinical Trials

1NTERACT

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This study is part of a collaborative effort to investigate weight management in young adults with Type 1 Diabetes, and to examine any barriers they may experience with regards to weight management or weight loss. Also, w ...

BNP

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The purpose of this study is to collect data to help researchers better understand the various causes of obesity which may lead to the development of obesity treatment options. Obesity is a major metabolic health concern ...

BNP 3

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To evaluate the safety and tolerability of Nesiritide (study drug) or placebo administered by continuous IV infusion for 48 hours in healthy obese subjects.

ISTAR-MICRO

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The purpose of this study is to collect data to examine whether short-term consumption of non-caloric artificial sweeteners (NCASs), such as saccharin, can lead to changes in your blood sugar levels and in the composition ...

ISTAR-T

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The purpose of this study is to find better ways to identify and treat pancreatic, hepatobiliary and gastrointestinal diseases, including cancer.

LADA

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Have you recently been diagnosed with diabetes? The purpose of this study is to further understand diabetes, specifically a form called Latent Autoimmune Diabetes in Adults (LADA), which tends to affect young to middle-ag ...

LIFE-DM

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The purpose of this study is to evaluate whether a culturally appropriate, comprehensive diabetes education and clinical program will improve glycemic control in an underserved population with diabetes mellitus. Life-DM e ...

ACME

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This study is currently enrolling.

Study Status: Active-Open Enrollment Study Name: ACME Study Focus: Patients with Type 1 Diabetes Study Contact: To learn more, please call 1-877-854-8475 or fill out Contact Us form.  Study Purpose: To develop a comprehen ...

BETA CELL T2D

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The purpose of this study is to better understand how cells that make insulin, known as beta cells, change in response to certain type 2 diabetes medications. Results from this study will help develop therapies to improve ...

TRIA

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Study Status: Active-Open to Enrollment Study Name: TRIA Study Focus: Investigational Medication Study Contact: To learn more, please call 1-877-854-8475 or fill out the Contact us form. Study Purpose: To evaluate the eff ...

WISDM

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To determine if CGM (FDA approved device that provides continuous insight into glucose levels) can reduce hypoglycemia and improve quality of life in older adults with Type 1 diabetes.

LX312

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This clinical research study is being conducted to evaluate the safety and potential effectiveness of an investigational ORAL product, given inTandem with your current insulin regumen for Type 1 diabetes.

LIGAND

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To evaluate the change from baseline in HbA1c during 12 weeks of treatment with 3 dose levels of study drug LGD-6972 compared to placebo in patients with T2DM.  This study will also evaluate the safety and tolerability of ...

IMPERIUM

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The purpose of this study is to help answer the question of which Type 2 diabetes treatment strategy is better. Participants will be randomized to one of two treatment strategies using FDA-approved medications currently u ...

BNP 2

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To evaluate the effects of short term intravenous infusion of Nesiritide (rhBNP) on resting metabolic rate in obese individuals

TRIALNET

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This study is currently enrolling.

Study Status: Active-Open to Enrollment Study Name: TrialNet Study Focus: Type 1 Diabetes Study Contact: To learn more, please call 1-877-854-8475 or fill out the Contact Us form. Study Purpose: To screen relatives of peo ...

PIONEER 4

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To compare the effectiveness and safety of once-daily dosing of an oral investigational product (semaglutide) versus liraglutide (Victoza®) versus placebo in individuals with Type 2 Diabetes.

PIONEER 5

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To compare the effect of once-daily dosing of 14 mg oral semaglutide versus placebo, in combination with metformin and/or sulfonylurea, basal insulin alone or metformin in combination with basal insulin in subjects with t ...

SUSTAIN 7

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When you have type 2 diabetes, the insulin produced by your body does not work properly. This causes blood sugar levels to be too high, which is harmful for the body. The purpose of this study is to compare the safety and ...

T1DIL-21

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To determine if a combination of an investigational drug called anti-IL-21 (NNC0114-0006) and a drug marketed for type 2 diabetes, called liraglutide, in addition to your standard treatment prescribed by your doctor, is a ...

DUET

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The purpose of this study is to assess the safety and tolerability of a non-FDA approved study drug SAR425899 and the effects of once a day dosing over 26 weeks while checking the blood sugar effects and comparing it to P ...

BETA CELL T1D

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An important goal of Type 1 Diabetes (T1D) research is to find ways to preserve or replace insulin secreting beta cells of the pancreas. Type 1 diabetes occurs when the immune system destroys these cells over time. While ...

ROF

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The purpose of this study is to determine if a study medication will help lower blood sugar levels and whether any affect may be different when taken with other medications.

D2D

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The purpose of this study is to evaluate the effect of taking vitamin D on the prevention of diabetes in people who may be at high risk for diabetes. This study is supported by the National Institutes of Health.

HONEY

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This study is currently enrolling.

The purpose of this study is to measure certain substances (biomarkers) in the body that may indicate triggers of Type 1 Diabetes to find a better way to diagnose the disease, as well its progression. 

STAMP

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This study is currently enrolling.

Study Purpose: The Study will evaluate an investigational drug treatment option for Non-alcoholic Fatty Liver Disease (NAFLD). To be enrolled in this study, you must meet certain requirements. You may be eligible to part ...

FLOW

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This study is currently enrolling.

Study Purpose: This research study will look at how well semaglutide works when compared to the ‘dummy medicine’ (placebo) in slowing the growth and worsening of diabetic kidney disease. To be enrolled in this study, you ...

SELECT

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This study is currently enrolling.

Study Purpose: This study will look mainly at the effect of semaglutide on cardiovascular events in patients who are overweight or obese and who have prior cardiovascular disease. To be enrolled in this study, you must m ...